A triangular bilingual learning model of “listening-discussion-presentation”, as well as a dynamic management model of “learning-feedback-revising” has been established in the course of microbiology with the assistance of Blackboard Learning System. Given the bilingual lecturing, well-developed discussion forum, and the teacher’s guidance both in classroom and online, students’ comprehensive performance and the results of postgraduate qualifying examination are both greatly increased. Students’ innovative ability is accordingly enhanced. Students who are for this synthesized reform account for 90 percent.