噬菌体及其裂解酶在食源性致病菌检测和控制中的应用

Application of bacteriophages and their lysins for detection and control of foodborne pathogens

摘要:

微生物致病菌引起的食源性疾病在全世界频频发生, 对人类健康造成严重危害, 尤其是致病菌耐药性的出现使常规治疗陷入困境。噬菌体及其编码的裂解酶的发现及应用, 为食源性致病菌的检测及生物防治开辟了新的途径。综述噬菌体及其裂解酶在构建食源性致病菌的快速检测方法和生物防治方面的应用。

关键词:噬菌体, 裂解酶, 食源性致病菌, 检测, 控制

Abstract:

The outbreaks of foodborne disease caused by foodborne pathogens are happened frequently and have a hazardous impact on public health, especially the emergence of antibiotic-resistant pathogens which may cause the failure of regular antimicrobial therapy. The discovery and application of bacteriophages and their lysins opened up a new path for detection and biocontrol of foodborne pathogens. This review intends to briefly summarize the application of bacteriophages and their lysins for constructing the rapid detection methods and biocontrol of foodborne pathogens.

Key words:Bacteriophages, Lysins, Foodborne pathogens, Detection, Control