Abstract:The integration of research and education is an important path for the integrated development of education, science & technology, and talents. It is the universal consensus for talent cultivation in first-class universities and an inherent requirement for the growth of innovative talents. The teaching team of Microbiology at Huazhong Agricultural University has explored a talent cultivation model based on the integration of research and education by continuously strengthening the supporting role of scientific research in improving teachers’ teaching abilities, the leading role of scientific frontiers and research culture in teaching resource construction, and the driving role of research practice in cultivating students’ innovative abilities. The mutual promotion between teaching and research has achieved good educational results.