Abstract:The bioeconomy is becoming an important force leading the development of strategic emerging industries. As an important field of bioeconomy, enzyme engineering face great opportunities and challenges in the future. We explore the teaching reform of Enzyme Engineering through the optimization of teaching target positioning, improvement of ideological connotation, condensation and reorganization of teaching contents, introduction of research and application hotspots, and design of diversified teaching and assessment modes. The teaching reform improves the teaching quality and student learning feedbacks. This paper provides valuable inspirations for cultivating enzyme engineering talents with rich professional knowledge, solid practical skills, and correct view of life values to meet the needs of national bioeconomic development.