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基于Web of Science的用于碳捕集的碳酸酐酶研究分析
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国家自然科学基金(42141008,42377203);国家重点研发计划(2022YFC2106000)


Analysis of carbonic anhydrase used for carbon capture based on Web of Science
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    摘要:

    【背景】目前碳酸酐酶(carbonic anhydrase,CA)被应用于医药、天然活性物筛选、生物检测和碳捕集等众多领域,虽然已发表了大量相关科研论文和著作,但尚缺乏对CA领域全面、系统的文献计量分析。【目的】深入挖掘和分析可应用于碳捕集的CA的研究动态、研究热点和发展趋势,为从事相关工作的研究者提供研究方向及数据参考。【方法】选用Web of Science (WOS)核心合集数据库作为数据源,利用VOSviewer作为文献计量工具,通过关键词分析、发文数量分析、国家分布、作者合作共现及机构合作共现等方式对CA领域热点和趋势进行分析。【结果】最终共筛选出795篇有效文献。国家之间合作综合排名第一的是美国。我国在该领域起步较晚,但近些年呈现出迅猛发展势头,目前已经领先于其他国家。在2004−2023年用于碳捕集的CA领域中,研究热点集中在CA的表达、功能、CA的抑制剂和CO2的捕集方面,随着时间的推移,通过分子对接筛选疾病靶点以及对CA的改造用于固碳已成为新的研究热点。【结论】CA用于碳捕集这一领域具有广阔的前景,本文以可视化的方式诠释了用于碳捕集的CA领域研究发展热点和趋势,为用于碳捕集的CA研究及其应用提供了重要参考。

    Abstract:

    [Background] At present, carbonic anhydrase (CA) is applied in many fields such as medicine, natural active substance screening, biological detection, and carbon capture. Although a large number of related scientific papers and works have been published, there is still a lack of comprehensive and systematic bibliometric analysis of the research progress in CA. [Objective] To deeply explore and analyze the research trends, research hotspots, and development trends of CA that can be applied in carbon capture and provide research directions and data references for researchers engaged in related work. [Methods] The core collection of Web of Science (WOS) was selected as the data source. VOSviewer was used to analyze the keywords, number of publications, country distribution, author co-occurrence, and institution co-occurrence, thereby revealing the research hotspots and trends of CA. [Results] A total of 795 valid publications were ultimately selected. The United States ranked first in comprehensive cooperation among countries. China started relatively late in this field, but has shown rapid development in recent years and is currently ahead of other countries. From 2004 to 2023, the research hotspots of CA for carbon capture focused on the expression, function, and inhibitors of CA and CO2 capture. Over time, screening disease targets through molecular docking and modifying CA for carbon sequestration have become new research hotspots. [Conclusion] The application of CA in carbon capture has broad prospects. This article visually explains the research and development hotspots and trends of CA that can be used for carbon capture, providing a theoretical basis for the research and application of CA for carbon capture.

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胡耀峰,程从雨,李为,余龙江. 基于Web of Science的用于碳捕集的碳酸酐酶研究分析[J]. 微生物学通报, 2025, 52(7): 3285-3301

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  • 收稿日期:2024-11-25
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  • 录用日期:2025-03-08
  • 在线发布日期: 2025-07-21
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