Abstract:As a globally important economic crop, the quality and growth of tobacco (Nicotiana tabacum L.) depends on the regulatory role of the symbiotic microbial community. Taking “core microbiome” as a starting point, we elaborate on the key roles of tobacco-related microorganisms: (1) as an important component of the tobacco holobiont, the composition of the tobacco core microbiome and its dynamic changes in different parts and developmental stages of tobacco; (2) the microbial community promoting nutrient acquisition, enhancing stress resistance, and regulating growth to maintain the health of tobacco crops; (3) the contribution of microbial activities, such as carbohydrate degradation and alkaloid conversion, to the formation of tobacco flavor during post-harvest processes like curing, fermentation, and aging. Prospects require integrating multi-omics and field experiments to elucidate the functional mechanisms of tobacco core microbiome, aiming to develop targeted regulatory strategies. This review provides a theoretical basis for optimizing tobacco cultivation and quality through microbiome regulation, providing scientific guidance for tobacco production.
