唾液微生物组在法庭科学领域中的应用

Application of salivary microbiome in forensic science

摘要:

随着分子生物学和生物信息学的发展，微生物组分析逐渐受到了法医学家的广泛关注。唾液作为口腔分泌液，集合了口腔多个位点的特征，其分泌还受到个体自身的影响，进行微生物组分析能够准确获得宿主的相关信息，具备了应用于法庭科学领域办案的前景。因此，本文基于唾液微生物组成及常用表征手段进行详细介绍，并综述了近年来唾液微生物组在法庭科学领域中的研究进展(包括体液鉴定、行为信息及个体识别的应用)，以期帮助研究者更好地了解唾液微生物组在法庭科学领域中的应用，正确把握研究方向。

Abstract:

With advancements in molecular biology and bioinformatics, microbiome analysis has garnered increasing attention from forensic scientists. Saliva, an oral secretion, integrates characteristics from multiple oral sites and is influenced by individual factors. Microbiome analysis can accurately yield the host information, showing promise for application in forensic science. This article details the composition characteristics and the characterization methods of the salivary microbiome and reviews the research progress in the applications of the salivary microbiome in forensic science (body fluid identification, behavioral information, and individual identification) in recent years. The aim is to help researchers better understand the application of the salivary microbiome in forensic science and to correctly grasp research directions.