我国微生物蛋白产业发展现状、挑战及趋势
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1国家开发投资集团有限公司,北京 100034;2国投生物制造创新研究院有限公司,北京 100034;3国投生物制造创新院研究院(无锡)有限公司,江苏 无锡 214122

作者简介:

张明灿:文献调研、框架设计、稿件撰写及修改;薛晓舟、王梦、张宁宁:文献整理、提出修改建议;李寅:监督指导、稿件润色修改。

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Current status, challenges, and trends of China’s microbial protein industry
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1State Development and Investment Group Co., Ltd., Beijing 100034, China;2SDIC Institutes for Biomanufacturing Innovation Co., Ltd., Beijing 100034, China;3SDIC Institutes for Biomanufacturing Innovation (Wuxi) Co., Ltd., Wuxi 214122, Jiangsu, China

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    摘要:

    面对全球人口增长带来的蛋白质供需矛盾以及传统农业生产模式的资源环境约束,发展高效、可持续的新型蛋白资源是践行大食物观、保障国家粮食安全和满足人民美好生活需要的重要方向。微生物蛋白,作为利用微生物细胞工厂生产菌体蛋白或特定功能蛋白的新型生物制造产品,因其生产效率高、原料适应性强而备受关注。本文系统综述了菌体蛋白及功能蛋白的最新研究进展与产业发展现状,分析了从菌种创制、工艺放大到产品应用开发的关键核心技术,以及在产业化进程中面临的成本结构、市场监管与消费者接受度等多重挑战。最后,展望了微生物蛋白在饲料替代、食品创新及医药和化妆品等高附加值领域的发展前景。本文为我国微生物蛋白产业的技术创新、产业布局与政策制定提供了系统性参考,助力产业高质量发展。

    Abstract:

    Facing the protein supply-demand contradiction brought about by global population growth and the resource and environmental constraints of traditional agricultural production models, developing efficient and sustainable new protein sources has become a major strategic direction for practicing the all-encompassing approach to food, ensuring national food security, and meeting the people’s needs for a better life. Microbial proteins, as a new type of biomanufacturing products (microbial protein or specific functional proteins) produced by microbial cell factories, have attracted much attention due to the high production efficiency and strong adaptability to raw materials. This article systematically reviews the latest research progress and industrialization status of microbial protein and functional protein in the food and pharmaceutical fields, analyzes the key technologies from strain creation, process scale-up to product application development, as well as the multiple challenges of cost structure, market regulation, and consumer acceptance faced in the industrialization process. Finally, this article makes an outlook on the prospects of microbial protein in high-value fields such as feed replacement, food innovation, pharmaceuticals, and cosmetics. It aims to provide a systematic reference for technological innovation, industrial layout, and policy formulation in China’s microbial protein industry and to assist in the high-quality development of the industry.

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张明灿,薛晓舟,王梦,张宁宁,李寅. 我国微生物蛋白产业发展现状、挑战及趋势[J]. 生物工程学报, 2026, 42(6): 2384-2396

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  • 收稿日期:2026-02-09
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  • 在线发布日期: 2026-06-24
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