We review briefly the strategies and processes to identify Ser/Thr protein kinases from Streptomycesspp. and discussed in detail the functions of well studied Ser/Thr protein kinases, such as AfsK. We used bioinformatic methods to predict transmembrane regions in Ser/Thr protein kinases of S. coelicolor A3(2) and S. avermitilis. The complete sets of Ser/Thr protein kinases from genomes of Streptomyces coelicolor A3(2) and Streptomyces avermitilis MA-4680 were categorized based on domain analyses.
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Xu Yang, Dongming Guan, Shenglan Wang. An update of Streptomyces eukaryotic-type Ser/Thr protein kinases--A Review. [J]. Acta Microbiologica Sinica, 2008, 48(1): 126-131