Molecular determinants in regulating Pseudomonas aeruginosa typeⅢsecretion system—— A review

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Molecular determinants in regulating Pseudomonas aeruginosa typeⅢsecretion system—— A review
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Fund Project:Supported by the National Natural Science Foundation of China (30500025), the Scientific Research Foundation for the Returned Overseas Chinese Scholars of State Education Ministry and the Construction Fund for “211” Project of the Ministry of Education of

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Abstract:

Pseudomonas aeruginosa is a Gram-negative opportunistic bacterial pathogen. Successful injection of virulence factors into host cells, evasion of phagocytosis and promotion of pathogenesis depend primarily on the function of type III secretion system (T3SS). A complex set of signaling pathways have been shown to modulate T3SS expression. In this review, a brief introduction is given on the composition, function, and molecular determinants that regulate P. aeruginosa T3SS gene expression.

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Qin Luo, Shouguang Jin. Molecular determinants in regulating Pseudomonas aeruginosa typeⅢsecretion system—— A review. [J]. Acta Microbiologica Sinica, 2008, 48(10): 1413-1417

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