amongAnimal-associated Pathogens-a review
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Supported by the Guangdong Provincial Natural Science Foundation(06201654)

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    Abstract:

    Abstract: Quorum sensing (QS) is a phenomenon that microbes regulate some of their genes by signals related to the density of population. It is confirmed that acyl-homoserine lactones (AHL), some peptides, some furanones and some other small moleculars can be used as quorum-sensing signals by microbes. Microbes control their physiology with different QS systems in parallel or hierarchical ways. A lot of microbial pathogenesis connect with quorum sensing closely. More and more studies show that QS systems regulate in microbial pathogenesis through the following points: (1) QS helping pathogens invasion and colonization; (2) QS regulating production of virulent factor; (3) QS giving pathogens the ability of immunity or drug resistance. We review the role of QS in microbial pathogenesis and address a new way to prevent and control microbial diseases.

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Qingping Wu, Kui Wu, Yingyang Ye, Xiaohui Dong, Jumei Zhang. amongAnimal-associated Pathogens-a review. [J]. Acta Microbiologica Sinica, 2009, 49(7): 853-858

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  • Received:December 28,2008
  • Revised:February 23,2009
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