Candida-epithelial interactions

Abstract:

Candida normally colonizes mucosal surfaces without causing any problems. Sometimes, it causes mucosal infections such as oropharyngeal candidiasis and vulvovaginal candidiasis in individuals with compromised immunity or microecological imbalance. For the treatment of the infections, antifungal agents are indispensable, and the host՚s immunity, especially mucosal epithelial cells as the first line of defense against Candida infection, plays an important role. In this paper, we summarize the research on the Candida-epithelial interactions.