Research progress of drugs and vaccines against enterovirus 71

Abstract:

Hand-foot and mouth disease (HFMD),as a disease of global concern,occurs frequently in Asia and its harm cannot be underestimated.The multiple transmission routes,strong infectivity,induction of complications,diverse pathogenic strains and easy variation bring challenges to the prevention and treatment of HFMD.Enterovirus 71(EV71) is one of the main pathogens causing HFMD.Since there is no specific drug against EV71,it is of great significance to find appropriate therapeutic drugs.We summarize the research progress of drugs and vaccines against EV71,aiming to give insights into the prevention and control of HFMD.