Adaptation mechanism of Brevibacterium species to the marine environment based on pan-genomics analysis

Abstract:

[Objective] Our main goal was to clarify the adaptation mechanism of Brevibacterium species to the marine environment.[Methods] In this paper, six Brevibacterium strains isolated from different sea regions and belonging to different operational taxonomic units were sequenced, assembled and annotated. Combined with the genomic data of 23 typical and atypical Brevibacterium strains downloaded from NCBI, pan genomics analysis and species evolution analysis were carried out.[Results] Pan genomics analysis showed that the Brevibacterium strains had an open pan genome, which was consistent with the diversity of its living environment. There are obvious differences between marine Brevibacterium strains and other habitat Brevibacterium strains at the genomic level, mainly in the aspects of gene family expansion and contraction, transporter family, metabolic pathway and CRISPR.[Conclusion] These differences at the genomic level preliminarily revealed the adaptability of marine Brevibacterium strains to marine environment, which laid the foundation for a deep-going understanding of the environmental adaptation mechanism of Brevibacterium strains.