Abstract:Enzymes catalyze most biochemical reactions in living organisms, and the high efficiency, chemo-, regio- and stereoselectivity make enzymes appealing catalysts in many fields. The digitalization of enzyme-related information is of great importance to both academic research and industrial applications. Microbial enzyme resource databases establish foundations for the mining, engineering, and utilization of new biocatalysts. This mini-review will briefly introduce the current development of enzyme databases and discuss the enzyme resources applications facilitated by databases.