Abstract:Autotrophic microorganisms can use inorganic carbon as a carbon source to synthesize their own nutrients, which have strong environmental adaptability and play an important role in the carbon fixation of the soil in the karst area rich in calcium and alkali. This review focuses on the process of autotrophic carbon fixation driven by soil microorganisms, the carbon fixing functional microorganisms in karst soils, and the molecular mechanisms of soil microbial autotrophic carbon fixation and their eco-environmental effects in karst area. The key scientific problems to be solved are also proposed. It provides a reference for further study and understanding the carbon sequestration process and its mechanisms driven by autotrophic microorganisms in the soil ecosystem of karst areas, improving the carbon sequestration potential of soil in karst areas, developing the protection and restoration strategies of karst ecological environment, and coping with the risk of soil degradation caused by climate change and human activities.