Abstract:Oxygen heterocycles are a kind of refractory organic pollutants commonly found in polluted environments. These compounds are of immense concern from point view of the environment because they are known for their toxic and carcinogenic properties. Here, we review the research progress in the biodegradation of typical oxygen-containing monoheterocyclic compounds tetrahydrofuran, 1,4-dioxane and oxygen-containing fused heterocyclic compounds dibenzofuran and dibenzo-p-dioxin. We address the degradation performance of bacteria, the degradation pathways and degradation-related genes. In addition, we discuss the research status of dioxins, and propose further research directions of biodegradation of oxygen heterocycles and their dioxin derivatives.