Research progress in transcriptional regulation of prodigiosin biosynthesis in Serratia marcescens

Abstract:

Prodigiosin is a red pigment with multiple biological activities, and of great economic value with promising application. Serratia marcescens is a major producer of prodigiosin, and the model organism for prodigiosin biosynthesis research. This paper reviews recent progresses in transcriptional regulation of prodigiosin synthesis in S. marcescens, illustrating the function of two/multiple component system, quorum sensing system, σ factor and transcriptional regulator in modulating prodigiosin biosynthesis. Moreover, further research focuses are discussed.