Genetic modification and application of lignocellulose degrading fungus

Abstract:

Conversion from lignocellulose to biofuel with enzyme hydrolysis will be beneficial for sustainable development. Most microorganisms used in the industrial production of cellulase are filamentous fungi. However, isolation of cellulase hyper producing strain is limited by the lack of proven technology on genetic modification of filamentous fungi and the mechanism of cellulase synthesis. In this paper, recent progress in the genetic modification of cellulase hyper producing strains are summarized. Specially, we discussed the influences of signal induction, signal transduction and transcriptional regulation on cellulase synthesis in filamentous fungi. Finally, the industrial application of filamentous fungi was also introduced.