Research progresses in human gut virome

Abstract:

Human Microbiome Project has been initiated for 10 years. Many studies revealed the crucial roles of human microbiome in human health and diseases. Human virome including human viruses and bacterial phages is a key component of human microbiome and can be associated with human health. Here, by reviewing the latest research progresses in human gut virome studies, we show the features of human gut virome, interactions between human virome, bacteriome and human cells, impacts on human health, as well as strategies and challenges in human gut virome study. We further explore the feasibility in using human gut virome for medical applications.