Antimicrobial resistance and dissemination of multidrug resistant organisms-A review

Abstract:

The abuse of antimicrobial agents has led to the rapid dissemination of multidrug resistant bacteria around the world. The multidrug resistant organisms (MDRO) and antibiotic resistance genes (ARGs) can be transferred among humans, animals and environments. Especially, ARGs can be transferred through a horizontal manner between the same species or different species of bacteria, making the growing problem of bacterial resistance and resistance mechanisms more complex. Moreover, the multidrug resistant organisms with complex resistance patterns have posed an increasing threat to our health. Therefore, the use of antibiotics must be tightly regulated.