Advances in integrase regulations of bacteria－A review

doi:10.13343/j.cnki.wsxb.20150007

Home > Archive>Volume 55, Issue 10, 2015 >1231-1237. DOI:10.13343/j.cnki.wsxb.20150007

Advances in integrase regulations of bacteria－A review
DOI:
                        10.13343/j.cnki.wsxb.20150007
                    
CSTR:
                        32112.14.j.AMS.20150007
                    
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Fund Project:Supported by the National Natural Science Foundation of China (31170112)， the National Science and Technology Major Project (2013ZX10004217-003)，the Life Sciences Student Training Program，and the State Key Laboratory of Microbial Technology，Shandong University．

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Abstract:

Abstract:Because the integrase of class 1 integron in bacteria has been demonstrated closely relative with antimicrobial resistance，we summarize in this review the discussions on some regulation factors with expression of the integrase，such as antibiotics，carbon catabolite repression (cAMP-CＲP complex)，the promoter of gene cassette variants (Pc-P2 combinations)，attC sites，some nucleotide-associated proteins，and the length of variable region． Furthermore，we also provide knowledge of the regulation mechanism of integrase，as well as insight into controlling the dissemination of antimicrobial resistance in the environments．

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Runze Ouyang, Yanyan He, Hai Xu. Advances in integrase regulations of bacteria－A review. [J]. Acta Microbiologica Sinica, 2015, 55(10): 1231-1237

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Received:January 07,2015
Revised:March 13,2015
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Online: September 29,2015
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