Carbohydrate metabolism and lactic acid biosynthesis of Lactococcus lactis subsp.lactis KLDS4.0325
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Supported by the National Natural Science Foundation of China (31171717),by the National Programs for High Technology Research and Development of China (2012AA022108) and by the Synergy Innovation Center of Food Safety and Nutrition of China

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    Abstract:

    Abstract:[Objective]We aimed to study the carbohydrate metabolism and lactic acid biosynthesis of Lactococcus lactis KLDS4.0325.[Methods]Whole genome shot gun strategy was used for genome sequencing of strain L.lactis KLDS 4.0325.Then,using bioinformatics method,we compared a series of protein-coding genes involved in transporting extracellular carbohydrate,sugar metabolism and lactic acid biosynthesis of strain L. lactis KLDS4.0325 with other 9 reference strains.[Results]In L.lactis KLDS4.0325 genome,where possesses more key enzyme coding genes related to the whole pathway of sugar metabolism than reference strains.[Conclusion〗In gene level,therefore,strain L.lactis KLDS4.0325 shows a remarkable characteristic by utilizing various sugar to produce lactic acid,is a lactic acid bacteria with industrial potential of high yield L-lactic acid.

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Xiaochun Yang, Yutang Wang, Ying Zhou, Xiaofeng Gao, Bailiang Li, Guicheng Huo. Carbohydrate metabolism and lactic acid biosynthesis of Lactococcus lactis subsp.lactis KLDS4.0325. [J]. Acta Microbiologica Sinica, 2014, 54(10): 1146-1154

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History
  • Received:January 03,2014
  • Revised:April 03,2014
  • Adopted:
  • Online: September 29,2014
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