Acid stress response of Salmonella and its relationship with virulence-A review

doi:10.13343/j.cnki.wsxb.2014.04.002

Home > Archive>Volume 54, Issue 4, 2014 >367-375. DOI:10.13343/j.cnki.wsxb.2014.04.002

Acid stress response of Salmonella and its relationship with virulence-A review
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                        10.13343/j.cnki.wsxb.2014.04.002
                    
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Fund Project:Supported by the National Natural Science Foundation of China (31270173) and by the Key Project of China National Programs for Fundamental Research and Development (2009CB522605)

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Abstract:As successful enteric bacteria，Salmonella spp．has to overcome the extreme acid condition in the stomach before invading into host intestinal epithelial cells．Salmonella spp． has evolved an adaptation to its replicative niche in the acidic environment． This review summarizes acid resistant characteristics of Salmonella，and introduces several mechanisms to acid resistance，including keeping internal pH homeostatic，synthesizing acid shock protein through several regulatory pathways and altering membrane character．The achievements will be significant for understanding and controlling Salmonella infections in the future．

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Jie Ren, Mingwen Zhao, Yufeng Yao. Acid stress response of Salmonella and its relationship with virulence-A review. [J]. Acta Microbiologica Sinica, 2014, 54(4): 367-375

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Received:July 16,2013
Revised:October 13,2013
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Online: April 01,2014
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