Influence of autophagy on elimination and proliferation of intracellular bacteria—A review

Abstract:

Abstract:Autophagy in intracellular bacterial infection is important． Host cells can use autophagy to eliminate invading pathogens． Meanwhile，autophagy can be exploited，modified or interfered by some pathogens to benefit their survival or proliferation． We reviewed the effect of autophagy on intracellular bacterial infection and discussed our study on the relationship between autophagy and Salmonella infection，which can help provide the theoretical basis for controlling pathogenic infection through regulating and exploiting autophagic pathway．