Next-generation sequencing technologies and the application in microbiology - A review

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Next-generation sequencing technologies and the application in microbiology - A review
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Fund Project:Supported by the State Key Development Program for Basic Research of China (2009CB522600) and by the National Key Program for Infectious Diseases of China (2008ZX10004-009).

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Abstract:

Abstract: Since its invention in 1970s, nucleic acid sequencing technology has contributed tremendously to the genomics advances. The next-generation sequencing technologies, represented by Solexa from Illumina, SOLiD from Applied Biosystems and 454 from Roche, re-energized the application of genomics. In this review, we first introduced the next-generation sequencing technologies, then, described their potential applications in the field of microbiology.

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Nan Qin, Dongfang Li, Ruifu Yang. Next-generation sequencing technologies and the application in microbiology - A review. [J]. Acta Microbiologica Sinica, 2011, 51(4): 445-457

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Received:September 15,2010
Revised:October 22,2010
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Online: February 02,2012
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