Antimicrobial peptides Peptaibols from Trichoderma－A review

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Antimicrobial peptides Peptaibols from Trichoderma－A review
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Fund Project:Supported by the National Natural Science Foundation of China (30870047), by the National High Technology Research and Development Program of China (2007 AA091504), by the Science Foundation for Middle–aged and Young Scientists of Shandong Province (BS2009SW045) , by the Science Foundation for Doctors of University of Jinan (XBS0824) and by the Science Foundation of University of Jinan (XKY1017)

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Abstract:

Astract: Peptaibols are a family of antimicrobial peptides, which are synthesized by non-ribosomal peptide synthetases (NRPS) and contain high proportions of α-aminoisobytyric acid (Aib). Up to now, 317 peptaibols have been identified, and the majority of them are produced by Trichoderma strains. In this review, we described the diversity, fermation, purification, identification and biosynthesis of peptaibols from Trichoderma.

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Xiaoyan Song, Yuzhong Zhang, Yuanxiu Wang. Antimicrobial peptides Peptaibols from Trichoderma－A review. [J]. Acta Microbiologica Sinica, 2011, 51(4): 438-444

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Received:September 13,2010
Revised:December 11,2010
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Online: February 02,2012
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